METHOD FOR PREDICTING OUTCOMES antiviral therapy of chronic hepatitis B

摘要

A method for predicting outcome of antiviral therapy of chronic hepatitis B, comprising the immunological study of blood, characterized in that the patient is determined in the blood concentration of α-interferon serum and induced α-interferon, spleen echography operate by measuring the magnitude of its cross-section; value calculated by the discriminant function formuleDF = 5,3769x-0,8186x-0,4369x, wherein the discriminant function value DF-; x- section spleen mm; x- concentration of α-interferon serum, IU / ml; x- concentration α- interferon-induced, IU / ml; 5.3769; -0.8186 and -0.4369 - discriminant function coefficients, is compared with a constant equal to 296.1005 and a value of a discriminant function 296.1005 predict relapse and less than or equal to 296.1005 predict response upon resistant value of the discriminant function after standard antiviral therapy of chronic hepatitis B.