METHOD FOR ROSUVASTATIN CORRECTION OF BONE MICROCIRCULATION IN EXPERIMENTAL OSTEOPOROSIS AND ACCOMPANYING FRACTURES

摘要

FIELD: medicine.;SUBSTANCE: method involves simulating osteoporosis in Wistar female rats by a bilateral ovariectomy and osteoporotic changes and pharmacological correction of pathological conditions with rosuvastatin 0.86 mg/kg intragastrically daily in a single dose once a day.;EFFECT: using the method enables increasing the bone blood supply that promotes delaying osteoporosis and creating the favourable environment for the fracture union.;1 ex