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DIAGNOSTIC TECHNIQUE FOR BREAST CANCER

机译:乳腺癌诊断技术

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, particularly to oncology, and aims at sub-typing breast cancer. RIL (PDLIM4) expression is measured in a patient's tumour tissue sample by the sequencing technology of the following NGS generation or by northern hybridisation methods and real-time PCR. If the RIL (PDLIM4) expression tends to decrease twice as much as its level in the normal tissues, a sub-type of a malignant breast new growth is diagnosed.;EFFECT: invention provides effective diagnostic technique for breast cancer subtype - tumours characterised by incomplete epithelial-mesenchymal transition and relatively minimally invasive.;2 dwg, 1 ex
机译:领域:药物。发明:发明是指医学,特别是涉及肿瘤学,旨在亚型化乳腺癌。 RIL(PDLIM4)表达是通过下一代NGS测序技术或Northern杂交方法和实时PCR在患者的肿瘤组织样品中测量的。如果RIL(PDLIM4)表达趋于下降至正常组织水平的两倍,则诊断出一种恶性乳腺新生长的亚型。效果:本发明为乳腺癌亚型提供了有效的诊断技术-特征在于肿瘤不完全的上皮-间质转化和相对微创。; 2 dwg,1 ex

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