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ARALKYL BENSYL ETHERS, METHODS OF SYNTHESIS THEREOF, INTERMEDIATE COMPOUNDS AND THEIR USE, METHODS FOR TREATMENT AND/OR PREVENTION, PHARMACEUTICAL COMPOSITION AND DRUG ON BASIS OF THESE COMPOUNDS
ARALKYL BENSYL ETHERS, METHODS OF SYNTHESIS THEREOF, INTERMEDIATE COMPOUNDS AND THEIR USE, METHODS FOR TREATMENT AND/OR PREVENTION, PHARMACEUTICAL COMPOSITION AND DRUG ON BASIS OF THESE COMPOUNDS
FIELD: chemistry.;SUBSTANCE: invention relates to organic chemistry, specifically to bensyl aralkyl ether of formula or to its pharmaceutically acceptable salt, where: Ar represents imidazolil; R1, R2, R4 and R5 independently stand for hydrogen; R3 stands for a halogen; R6 stands for trifluoromethyl or trichloromethyl; n is an integer from 0 to 2; and m is 1. The invention also relates to the use of the compound of formula (1) for the treatment and/or prevention of diseases caused by fungi, or bacteria.;EFFECT: obtained new heterocyclic compounds with useful biological properties.;4 cl, 4 dwg, 9 tbl, 8 ex
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机译:技术领域本发明涉及有机化学,尤其涉及式<图像文件=“ 00000029.GIF” he =“ 64” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 43” / >或其药学上可接受的盐,其中:Ar代表咪唑唑; R 1 Sub>,R 2 Sub>,R 4 Sub>和R 5 Sub>独立地代表氢; R 3 Sub>代表卤素; R 6 Sub>代表三氟甲基或三氯甲基; n是0至2的整数;本发明还涉及式(1)的化合物在治疗和/或预防由真菌或细菌引起的疾病中的用途。效果:获得了具有有用生物学特性的新型杂环化合物; 4 cl,4 dwg,9 tbl,8 ex
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