METHOD OF PREDICTING PROTRACTED COURSE OF ACUTE RHINOPHARYNGITIS IN WOMEN WITH REACTIVATION OF CHRONIC CYTOMEGALOVIRAL INFECTION IN SECOND TRIMESTER OF PREGNANCY

摘要

FIELD: medicine.;SUBSTANCE: titre of IgM antibodies to cytomegalovirus (CMV) and titres of IgG antibodies to CMV in paired blood serums are determined in points (1 point - titres of IgM antibodies to CMV 1:200 and titres of antibodies IgG to CMV 1:200 - 1:400 with avidity index JgG to CMV higher than 65% in paired blood serums; 2 points - titre of IgM antibodies to CMV 1:400 and titres of IgG antibodies to CMV 1:400-1:800 with IgG avidity index to CMV higher than 65% in paired blood serums; 3 points - titre of IgM antibodies to CMV 1:400 and titres of IgG antibodies to CMV 1:200 - 1:800 with IgG avidity index to CMV higher than 65% in paired blood serums) (A), concentration of interferon -γ(pg/ml) in blood serum in the period of disease height of disease (B). After that, protracted course of acute rhinopharyngitis is determined by means of discriminant equation, including determined indices, D. If D value is lower than boundary value of discriminant function, absence of protracted course of acute rhinopharyngitis in women in case of reactivation of chronic cytomegaloviral infection in second trimester of pregnancy is predicted. If D is equal or is higher than boundary value, development of protracted course of acute rhinopharyngitis in women in case of reactivation of chronic cytomegaloviral infection in second trimester of pregnancy is predicted.;EFFECT: invention provides prediction of protracted course of acute rhinopharyngitis in case of reactivation of chronic cytomegaloviral infection in women in second trimester of pregnancy.;2 ex