DETERMINATION OF CELL SENSITIVITY TO TREATMENT WITH B-Raf INHIBITOR BY DETECTION OF K-ras MUTATION AND LEVELS OF RTK EXPRESSION

摘要

FIELD: medicine.;SUBSTANCE: invention relates to field of medicine. Claimed is method, including determination of presence or absence of K-ras^G12D mutation. Presence of K-ras^G12D mutation points to the fact that patient will not respond to treatment with B-Raf inhibitor.;EFFECT: invention provides effective method of identifying patient who does not respond to treatment with B-Raf inhibitor.;6 cl, 34 dwg, 12 tbl, 3 ex