METHOD FOR PRODUCING AND INDUCING TARGETED DIFFERENTIATION OF PULMONARY PLURIPOTENT CELL CULTURE

摘要

FIELD: medicine.;SUBSTANCE: invention refers to biotechnology and medicine. What is presented is a method for differentiation of mesenchymal stem cells of fibrotic lungs into fibroblastic cells, characterised by recovering the cells self-maintaining in vitro for 60 days and having mesenchymal stem cell phenotype (CD44⁺, CD73⁺, CD90⁺, CD106⁺, CD31^-, CD34^-, CD45^-) from the right lobe of fibrotic lungs and producing the fibroblastic cells when adding fibroblast growth factor 2 mcg/ml to the mesenchymal stem cell culture.;EFFECT: method enables producing the donor cells from the patients suffering idiopathic fibrosis from fibrotic pulmonary tissues.;3 dwg, 1 ex