VON WILLEBRAND FACTOR OR FACTOR VIII AND VON WILLEBRAND FACTOR FOR TREATMENT OF COAGULOPATHY, INDUCED BY PLATELET INHIBITORS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: group of inventions relates to the field of pharmaceutics and medicine and deals with the application of the von Willebrand factor in a combination with factor VIII for the treatment and/or prevention of a haemorrhage episode, associated with thrombopathy, induced with platelet-inhibiting substances, the where platelet-inhibiting substance is represented by an inhibitor of ADP receptor or a combination of the inhibitor of FDP receptor and cyclooxygenase inhibitor. The invention also relates to a composition and a method of treatment and/or prevention of a disorder, associated with the haemorrhage, associated with thrombopathy, induced by the platelet-inhibiting substances.;EFFECT: group of inventions provides the reduction or prevention of undesirable instances of the haemorrhage after the introduction of anticoagulants or fibrinolytics.;19 cl, 6 dwg, 5 tbl, 2 ex