PHARMACEUTICAL MUPIROCIN COMPOSITION FOR LOCAL APPLICATION

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention relates to the pharmaceutical industry and represents a water-free gel-like composition of mupirocin or its pharmaceutically acceptable salt for local application for the treatment of bacterial skin infections, containing a lipophilic base, selected from the group, consisting of vaseline, medium-chain triglycerides, isopropylmyristate and their mixtures, a bioadhesive, selected from the group, consisting of polyvinylpyrrolidone and polymethacrylates, and a solvent, selected from the group, consisting of ethanol, propanol and isopropanol.;EFFECT: provided is an increased time of the active ingredient presence in skin, which results in the reduction of the number of applications with the preservation of the clinical effect, as well as provides more effective treatment.;35 cl, 1 dwg, 8 tbl, 12 ex