A method for obtaining tormentillsäure from potentilla erecta

摘要

tormentillsäure is in all known natural starting materials in only very small amounts in free form. The extraction and workup by means of extensive yields achieved are low, since in many starting materials tormentillsäure carbon hydrate is bound and through the described extraction processes is detected is not sufficiently. The recovery of pure tormentillsäure thus turned out to be correspondingly complicated and expensive. It is therefore an object of the present invention to provide a process for obtaining pure from the tormentillsäure in a very high concentrations in various plants present to develop tormentosid.As a starting material, the roots of potentilla used erecta. By extraction with alcoholic solvents, subsequent alkaline saponification, neutralization with inorganic or organic acids, re - extraction with medium-polarity solvents and reprecipitation from alcohol / water - mixtures, by means of a simple chromatography on silica gel obtained analytically pure tormentillsäure.Use in pharmacy on the basis of a variety of therapeutic effects, such as, for example, antimicrobial, - tumor active and anti - inflammatory effect; anti - hiv - and - activity - malaria,).