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Test system of the evolution of a solid tumour by image analysis

机译:通过图像分析的实体瘤演变测试系统

摘要

The present invention relates to a method for predicting the evolution of a solid tumours in an individual, comprising at least the following steps: a) form a virtual blade from a sample of the tumor, on which an edge of the tumor is identifiable, b) quantify on said blade virtual carried out in step a) the density of the cells and / or in the blood vessels present in a continuous zone covering the edge of the tumor and extending on either side of the edge of the tumor over a distance at least equal to 0.5 mm, called "quantization zone ", and c) can be deduced from said quantification the risk of relapse patients post-operatively, and / or the sensitivity to the various treatments anti - tumour and / or the risk of hepatic metastases in the patient. Preferably, the cells to quantify are white blood cells, such as t lymphocytes, the b lymphocytes and macrophages and nk cells, dendritic cells, or under - populations of the immune cells.
机译:本发明涉及一种用于预测个体中实体瘤的演变的方法,该方法至少包括以下步骤:a)由肿瘤样品形成虚拟刀片,在其上可识别出肿瘤的边缘,b )量化在步骤a)中虚拟执行的刀片上的细胞和/或血管密度,该密度存在于覆盖肿瘤边缘的连续区域中,并在肿瘤边缘的任一侧延伸一定距离至少等于0.5毫米,称为“量化区”,并且c)可以从上述量化推论得出术后复发患者的风险,和/或对各种治疗方法的敏感性和/或肝转移风险在病人身上。优选地,要定量的细胞是白细胞,例如t淋巴细胞,b淋巴细胞和巨噬细胞以及nk细胞,树突细胞或免疫细胞的不足群体。

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