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AUTOLOGOUS TUMOR LYSATE-LOADED DENDRITIC CELL VACCINE FOR TREATMENT OF LIVER CANCER
AUTOLOGOUS TUMOR LYSATE-LOADED DENDRITIC CELL VACCINE FOR TREATMENT OF LIVER CANCER
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机译:自体肿瘤裂解物加载树突状细胞疫苗治疗肝癌
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摘要
The present disclosure provides compositions comprising mature dendritic cells loaded with autologous tumor cell lysates for the treatment of liver cancers, such as hepatocellular carcinoma. Hepatocellular carcinoma (HCC) is the fifth leading cancer and third leading cause of cancer-related mortality worldwide. Surgical resection and liver transplantation remain the mainstay of effective therapy for patients with early disease. However, a prevalent problem with HCC is the high likelihood of initial diagnosis at an advanced stage.
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