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USE OF SPHINGOID LONG CHAIN BASES AND THEIR ANALOGS IN TREATING AND PREVENTING BACTERIAL INFECTIONS

机译：类脂蛋白长链碱基及其类似物在治疗和预防细菌感染中的应用

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摘要

Methods of preventing or treating bacterial infections, including but not limited to Pseudomonas aeruginosa infections, by administering sphingoid long chain bases (LCB) are provided. The invention further relates to the use of sphingoid long chain bases, or pharmaceutical composition comprising same, for the treatment of lung diseases or disorders such as cystic fibrosis and chronic obstructive pulmonary disease.

机译：提供了通过施用鞘状长链碱基（LCB）来预防或治疗细菌感染的方法，包括但不限于铜绿假单胞菌感染。本发明进一步涉及鞘氨醇长链碱基或包含其的药物组合物在治疗肺部疾病或病症如囊性纤维化和慢性阻塞性肺部疾病中的用途。

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公开/公告号EP2906570A4

专利类型
公开/公告日2016-06-08

原文格式PDF
申请/专利权人 YEDA RESEARCH AND DEVELOPMENT CO. LTD.;UNIVERSITY OF DUISBURG-ESSEN;
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申请/专利号EP20130846807
发明设计人 FUTERMAN ANTHONY;PEWZNER-JUNG YAEL;GULBINS ERICH;
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申请日2013-10-15
分类号A61K9;A61K31/133;A61K31/137;A61K31/164;A61K31/225;A61K31/661;A61K31/662;A61K31/7028;A61P31/04;C07F9/09;C07F9/113;C07F9/141;C07F9/38;
国家 EP
入库时间 2022-08-21 14:51:12

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