A METHOD OF DIAGNOSIS OR PROGNOSIS OF A NEOPLASM COMPRISING DETERMINING THE LEVEL OF EXPRESSION OF A PROTEIN IN STROMAL CELLS ADJACENT TO THE NEOPLASM

摘要

The invention provides diagnostic and therapeutic methods for neoplastic disease patients with neoplasms of, for example, the breast, skin, kidney, lung, pancreas, rectum and colon, prostate, bladder, epithelial, non-epithelial, lymphomas, sarcomas, melanomas, and the like, wherein the method comprises determining the level of expression o caveolin-1, caveolin-2, vimentin, calponin2, tropomyosin, gelsolin, prolyl 4-hydroxylase alpha, EF-I -delta, or M2- isoform of pyruvate kinase in stromal cells adjacent to the neoplasm.