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NERVE-CELL-REGENERATING OR NERVE-CELL GROWTH-PROMOTING PHARMACEUTICAL COMPOSITION CONTAINING VAX PROTEIN AS ACTIVE INGREDIENT
NERVE-CELL-REGENERATING OR NERVE-CELL GROWTH-PROMOTING PHARMACEUTICAL COMPOSITION CONTAINING VAX PROTEIN AS ACTIVE INGREDIENT
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机译:含有VAX蛋白作为活性成分的神经细胞再生或神经细胞生长药物组合物
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摘要
The present invention relates to a nerve-cell-regenerating pharmaceutical composition containing Vax protein as an active ingredient, and, more specifically, the Vax protein can advantageously be used as a nerve-cell-regenerating pharmaceutical composition as it has been confirmed that Vax1 is secreted from a ventral hypothalamus (vHT) section isolated from the mouse and that, after the secreted Vax1 has been bound to extracellular sugar groups of heparan sulphate proteoglycans (HSPGs) present in retinal ganglion cell (RGC) axons of a co-cultured retinal section such that the product penetrates as axoplasm (axonplasm), the synthesis of local protein is activated and the growth of retinal ganglion cells (RGCs) is promoted.
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