首页>
外国专利>
SYSTEMS, METHODS, AND ENVIRONMENT FOR AUTOMATED REVIEW OF GENOMIC DATA TO IDENTIFY DOWNREGULATED AND/OR UPREGULATED GENE EXPRESSION INDICATIVE OF A DISEASE OR CONDITION
SYSTEMS, METHODS, AND ENVIRONMENT FOR AUTOMATED REVIEW OF GENOMIC DATA TO IDENTIFY DOWNREGULATED AND/OR UPREGULATED GENE EXPRESSION INDICATIVE OF A DISEASE OR CONDITION
展开▼
机译:用于自动审查基因组数据以鉴定疾病或病症的下调和/或上调的基因表达的系统,方法和环境
展开▼
页面导航
摘要
著录项
相似文献
摘要
The disclosure relates to systems and methods for automated review of genomic data to identify genetic features indicative of a particular disease or condition. The system accesses genomic data of a first cohort of individuals and identifies one or more genes each of which is differentially expressed by individuals in a group having the disease or condition compared with a control group. The system accesses single-nucleotide polymorphism (SNP) data of a second cohort of individuals different from the first cohort and identifies SNPs associated with the disease or condition. The system determines an intersection between the set of identified genes and the SNPs associated with the disease or condition to identify one or more genes that are downregulated due to the disease or condition. Related treatment methods are also included.
展开▼