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PLASMONIC NANOCAVITY ARRAY SENSORS FOR ANALYTE DETECTION ENHANCEMENT AND METHODS FOR MAKING AND USING OF THE SAME
PLASMONIC NANOCAVITY ARRAY SENSORS FOR ANALYTE DETECTION ENHANCEMENT AND METHODS FOR MAKING AND USING OF THE SAME
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机译:用于分析物检测增强的等离子纳氏阵列传感器及其制造和使用方法
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摘要
This disclosure provides, among other things, a method for enhancing detection of an analyte that is bound to a substrate comprising a signal amplification layer on a surface of the substrate, wherein the signal amplification layer comprises high-amplification regions and low-amplification regions, and the high-amplification regions amplify signals at said surface more than the low-amplification regions. The method comprises selectively masking the low-amplification regions of the substrate, thereby increasing the probability that an analyte will bind to a high-amplification region and be detected.
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