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TANDEM QUADRUPOLE MASS SPECTROSCOPY DEVICE

机译:串联四极质谱仪

摘要

A measurement condition memory (31) built in a controller (30) stores a CID gas condition table (31a) indicating a relation between the scan speed of a mass scan by a front-stage quadrupole mass filter (3) and a CID gas supply pressure. If the scan speed is high, an influence of a decrease in speed of ions due to collisions with a CID gas inside a collision cell (4) is relatively large. In view of this, such an appropriate CID gas supply pressure that reduces the decay of a peak waveform on a mass spectrum and makes the ion intensity as high as possible is examined in advance for each scan speed, and is stored in advance into the CID gas condition table (31a). During measurement of a target sample, if a precursor ion scan measurement mode or the like is designated, a CID gas supply pressure corresponding to the currently set scan speed is obtained based on the CID gas condition table (31a), and the CID gas supplier (8) is controlled. Accordingly, a mass spectrum with high peak separability and favorable sensitivity can be obtained regardless of the scan speed.
机译:控制器(30)中内置的测量条件存储器(31)存储CID气体条件表(31a),该表指示前级四极质量过滤器(3)进行质量扫描的扫描速度与CID气体供给之间的关系。压力。如果扫描速度高,则由于与碰撞室(4)内的CID气体碰撞而引起的离子速度降低的影响相对较大。鉴于此,对于每种扫描速度,预先检查适当的CID气体供应压力,以减少质谱图中峰波形的衰减并使离子强度尽可能高,并预先存储在CID中气体状况表(31a)。在目标样品的测量期间,如果指定了前驱体离子扫描测量模式等,则基于CID气体条件表(31a)获得与当前设置的扫描速度相对应的CID气体供应压力,以及CID气体供应商(8)被控制。因此,无论扫描速度如何,都可以获得具有高的峰分离性和良好的灵敏度的质谱。

著录项

  • 公开/公告号EP2921852A4

    专利类型

  • 公开/公告日2015-11-11

    原文格式PDF

  • 申请/专利权人 SHIMADZU CORPORATION;

    申请/专利号EP20120888305

  • 发明设计人 FUJITA SHINJIRO;

    申请日2012-11-13

  • 分类号H01J49/42;H01J49;

  • 国家 EP

  • 入库时间 2022-08-21 14:48:56

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