Monoclonal antibodies for the treatment of osteoporosis, multiple sclerosis and neoplastic diseases

摘要

An antibody or functional fragment thereof specifically blocking an epitope located on plexin-B1 for the binding of semaphorin to plexin-B1 that is located in the region of amino acids 20 to 534 of plexin-B1 is useful in the therapy of osteoporosis, multiple sclerosis and neoplastic diseases.