A BIOMARKER ALGORITHM FOR DETERMINING THE TIME OF STROKE SYMPTOM ONSET AND METHOD

摘要

A method of for determination include obtained from an individual biological sample provide stroke symptom onset time; Contacting the biological sample with a detection composition, it is included at least: LY96, ARG1, a CA4, and one TLR expression mediator one expression mediator, or the combination of these expression mediators, wherein express mediator at least one is related with an acute phase response of ischemic stroke, be used to form a detectable response; With the association in time detectable response of the beginning of one or more stroke symptoms. One composition, which provides, has a nucleic acid probe, the biomarker of an antibody or a purifying, specific to the combination of at least one or these expression mediators of LY96, ARG1, CA4 and TLR expression mediators.