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Biomarker algorithms and methods for determining the time of onset of stroke symptoms

机译:用于确定中风症状发作时间的生物标志物算法和方法

摘要

A step of obtaining a biological sample from a p- individuals; LY96, ARG1, CA4, and at least one expression mediators of TLR expression mediator or a detecting composition comprising a combination of these expression mediators, biologically the method comprising contacting the sample, but wherein at least one of said expression mediator, associated with acute phase response in ischemic stroke to form a detectable response, step; and a detectable response 1 One or more comprising the step of correlating the time of onset of stroke symptoms, provides a method of determining the time of onset of stroke symptoms. LY96, ARG1, CA4, and at least one of the TLR expression mediator, or is specific for a combination of these expression mediators, provides a nucleic acid probe, an antibody or purified composition with a biomarker.
机译:从->个人获得生物样品的步骤; LY96,ARG1,CA4和至少一种TLR表达介体或包含这些表达介体的组合的检测组合物的生物学方法包括接触样品,但其中至少一种与急性期相关的表达介体缺血性中风的反应,形成可检测的反应,步骤; 1和一个或多个包括使中风症状发作时间相关的步骤,提供了一种确定中风症状发作时间的方法。 LY96,ARG1,CA4和至少一种TLR表达介质,或对这些表达介质的组合具有特异性,可提供核酸探针,抗体或具有生物标志物的纯化组合物。

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