首页> 外国专利> CULTURE MEDIUM FOR DIFFERENTIATED CELLS DERIVED FROM STEM CELLS, PRODUCTION OF DIFFERENTIATED CELLS FROM STEM CELLS, AND METHOD FOR PRODUCTION OF CELL PHARMACEUTICAL COMPOSITION CONTAINING DIFFERENTIATED CELLS

CULTURE MEDIUM FOR DIFFERENTIATED CELLS DERIVED FROM STEM CELLS, PRODUCTION OF DIFFERENTIATED CELLS FROM STEM CELLS, AND METHOD FOR PRODUCTION OF CELL PHARMACEUTICAL COMPOSITION CONTAINING DIFFERENTIATED CELLS

机译:用于干细胞来源的分化细胞的培养培养基,用于干细胞来源的分化细胞的生产以及用于制备包含该细胞成分的药物成分的方法

摘要

PROBLEM TO BE SOLVED: To provide a technique of preparing differentiated cells without the contamination with undifferentiated stem cells, in differentiated cells induced from stem cells; and to provide a pharmaceutical composition containing a stem cell survival inhibitor for inhibiting in vivo neoplastic transformation of a cell pharmaceutical composition containing differentiated cells derived from stem cells.SOLUTION: The invention provides a culture medium for differentiated cells derived from stem cells by which differentiated cells without contamination with undifferentiated stem cells can be obtained by compounding, into the undifferentiated stem cells, atrovastatin which has a specific survival inhibiting activity and inhibits the survival of undifferentiated stem cells without inducing the apoptosis of the differentiated cells.SELECTED DRAWING: Figure 1
机译:要解决的问题:提供一种在未分化干细胞污染的情况下制备分化细胞的技术。并提供含有干细胞存活抑制剂的药物组合物,其用于抑制含有衍生自干细胞的分化细胞的细胞药物组合物的体内肿瘤转化。解决方案:本发明提供了用于衍生自干细胞的分化细胞的培养基,通过该培养基,分化细胞通过将具有特定的生存抑制活性并抑制未分化干细胞存活而不诱导分化细胞凋亡的阿托伐他汀复合到未分化干细胞中,可以得到未分化干细胞没有污染的方法。图1:

著录项

  • 公开/公告号JP2016093178A

    专利类型

  • 公开/公告日2016-05-26

    原文格式PDF

  • 申请/专利权人 KYOWA HAKKO KIRIN CO LTD;

    申请/专利号JP20150220829

  • 申请日2015-11-11

  • 分类号C12N1;C12N5/071;C12N5/22;A61P35;A61K31/40;A61K35/12;A61P43;A61K35/545;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 14:46:39

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