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Methods for propagating viruses using MDCK-derived cell lines and such cell lines in suspension culture in protein-free medium

机译:在无蛋白培养基中悬浮培养时使用MDCK衍生的细胞系和此类细胞系繁殖病毒的方法

摘要

present invention relates to novel MDCK-derived cell line capable of suspension culture in protein-free medium, and to produce vaccines using the MDCK-derived cell line to a method of growing the virus. The new MDCK-derived cell lines, higher for various viruses, showed uniform productivity, whereas a change in the antigenicity of the virus is small, has a low tumorigenic potential, therefore, the production of virus used in the vaccine It may be useful to.FIELD 6
机译:本发明涉及能够在无蛋白培养基中悬浮培养的新颖的MDCK来源的细胞系,以及使用MDCK来源的细胞系生产疫苗的方法。新型MDCK衍生的细胞系对各种病毒具有更高的生产力,显示出均一的生产力,而病毒的抗原性变化很小,致癌潜力较低,因此,疫苗中使用的病毒的生产可能对.FIELD 6

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