Prevention or reduction of chemotherapy-induced alopecia using vitamin D

摘要

The present invention provides methods and pharmaceutical compositions for preventing or reducing chemotherapy-induced alopecia (CIA). The pharmaceutical composition of the present invention comprises an effective amount of a vitamin D compound in a topical formulation. The present invention relates to chemotherapy for inducing alopecia, for example, cervical cancer, endometrial cancer, ovarian cancer, fallopian tube cancer, primary peritoneal cancer, soft tissue sarcoma, or osteosarcoma Has broad applicability in taxane-based chemotherapy. The pharmaceutical composition of the present invention can advantageously be administered prior to and / or concurrently with chemotherapy. [Selection] Figure 1