Treatment of childhood growth hormone deficiency with human growth hormone analogues

摘要

The present invention relates to a method for treating pediatric growth hormone deficiency (PGHD) for pediatric subjects. The treatment modifies pediatric patients with PGHD in a therapeutically effective dose of human growth hormone-XTEN (hGH-XTEN) fusion protein every week, every two weeks, every half month, every three weeks, or every month. Administration. This treatment is not inferior to the stature growth rate achieved using daily administration of hGH that is not bound to XTEN over the same period of time. In another embodiment, the dose is a bolus dose. [Selection figure] None