Composite carrier for immobilization of proteins, polypeptides, or oligopeptides, methods for their preparation, and applications

摘要

The present invention provides a complex carrier for immobilizing proteins, polypeptides, or oligopeptides, a method for preparing the same, and application. The composite carrier is a porous material, comprising: (1) a porous organic foam material comprising open pores; and (2) having an aldehyde group and one or more pore walls of the porous organic foam material. With a cross-linked product immobilized on the surface, where aldehyde groups can react with proteins, polypeptides, or oligopeptides, as well as aldehyde groups formed by chitosan via a cross-linking reaction with polyaldehyde compounds Is done. The disclosed composite carrier has several advantages and significant technical effects. In particular, proteins, polypeptides, or oligopeptides can be easily and stably immobilized. The immobilized product has a large specific surface area and a high specific activity. Immobilization is simple and low cost and suitable for industrial applications.