HDC activation inhibitor, HDC activation inhibitor composition, antipruritic agent and antipruritic composition

摘要

Provided are an HDC activation inhibitor and an antipruritic agent which are effective in animals against the itch caused by a itch generation mechanism different from the well-known one. An HDC activation inhibitor or antipruritic agent which is at least one member selected from (1) a particular flavonoid, (2) a tannin, (3) chlorogenic acid, (4) a particular stilbenoid, or a glucoside or pharmaceutically acceptable derivative of any of (1) to (4) given above, or (5) a particular crude drug extract, (6) walnut polyphenol.