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Devices and methods comprising the microelectrode array for conducting cell

机译:包括用于传导电池的微电极阵列的装置和方法

摘要

present invention, muscle cells (cardiomyocytes, skeletal muscle myocytes, and including, smooth muscle myocytes, but not limited to) the differentiation of conductive cells including a neural cell, maturation, and function of the analysis of It relates to a device and method including a micro-electrode array for. Microelectrodes present on the array, for stimulating cultured on substrates cells, and can be used for recording from the cells. In some embodiments, the substrate has a substantially smooth surface, and, in other embodiments, the substrate is, nano-textured (nanotextured), substantially nanometer wide-microns wide to provide a parallel grooves and ridges of the array.
机译:本发明涉及肌肉细胞(心肌细胞,骨骼肌肌细胞,包括平滑肌肌细胞,但不限于此)包括神经细胞在内的导电细胞的分化,成熟及其功能的分析。用于的微电极阵列。阵列上存在的微电极,用于刺激培养在底物细胞上的微电极,可用于从细胞中进行记录。在一些实施例中,衬底具有基本光滑的表面,并且在其他实施例中,衬底是纳米纹理化的(nanotextured),基本纳米宽度-微米宽的,以提供阵列的平行凹槽和脊。

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