Use of allogeneic stromal vascular layer cells and allogeneic mesenchymal progenitor cells in the prevention or treatment of osteoarthritis

摘要

The present invention relates to the use of heterologous stromal vascular layer cells and allogeneic mesenchymal progenitor cells in the prevention or treatment of osteoarthritis. Specifically, administration of a drug composition comprising heterologous stromal vascular layer cells and allogeneic mesenchymal progenitor cells of the xenogeneic origin of the present invention to a subject in need is significant prevention or osteoarthritis Has therapeutic effect. Allogeneic mesenchymal progenitor cells have a low immunogenicity, almost no heterogeneous immune rejection occurs, and safety of use is guaranteed. Allogeneic mesenchymal progenitor cells have a high cytokine secretion ability and can repair biological damage. In addition, it has the ability of chondrogenic differentiation and ossification. The present invention also provides a drug composition comprising allogeneic stromal vascular layer cells and allogeneic mesenchymal progenitor cells, and a method for preventing and treating osteoarthritis.