Methods and compositions for improving the efficacy of suboptimally administered medication and / or reducing side effects

摘要

The present invention provides methods and compositions for improving the effectiveness of suboptimally administered drug therapy and / or for reducing side effects. The present invention relates to methods and compositions for improving the therapeutic effects of previously limited therapeutic agents by suboptimal therapeutic action. The improvement is done by improving the utility of a single therapy or reducing side effects. Such methods and compositions are particularly applicable to mustard-based alkylating agents such as uracil mustard and their analogs, derivatives or prodrugs including 6-methyluracil mustard and 6-ethyluracil mustard It is.