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Diphenyl ether compounds for the treatment of liver, lung disorders, diabetic complications and cardiovascular diseases
Diphenyl ether compounds for the treatment of liver, lung disorders, diabetic complications and cardiovascular diseases
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机译:用于治疗肝,肺疾病,糖尿病并发症和心血管疾病的二苯醚化合物
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摘要
Described herein are compounds of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof, for use in treating liver diseases such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), and other fibrotic diseases of the liver; diabetic complications such as macro (ischemic heart disease, cerebrovascular disease and peripheral vascular disease) and micro (cataract, retinopathy nephropathy neuropathy, maculopathy and glaucoma) vascular complication; and cardiovascular diseases such as atherosclerosis, restenosis, hypertension, vasospasm, and cardiac hypertrophy; and lung disorders and lung fibrosis.
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