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Infusion solution for peripheral intravenous administration formulation

机译:外周静脉给药制剂的输液

摘要

PROBLEM TO BE SOLVED: To provide a stable infusion preparation for peripheral intravenous administration that can be stably preserved at normal temperature, can maintain/improve a nutritional state of a patient whose nutritional state of vitamins such as vitamin B1, vitamin C and the like is expected to deteriorate or has deteriorated, and can further exhibit an antioxidative stress action effectively.;SOLUTION: An infusion preparation for peripheral intravenous administration comprises an infusion liquid (A) containing a saccharide in a concentration of 70 to 150 g/L and an infusion liquid (B) containing an amino acid in a concentration of 50 to 150 g/L, which are separately accommodated in a container divided by communicable dividing means. The infusion liquid (A) does not contain a sulfite salt but contains vitamin B1 and has a pH of 3 to 5. At least either one of the infusion liquid (A) and the infusion liquid (B) contains vitamin C, and a mixed liquid of the infusion liquid (A) with the infusion liquid (B) is set to have a concentration of vitamin C of 200 to 400 mg/L and to give a daily dosage of vitamin C of 400 to 800 mg.;COPYRIGHT: (C)2015,JPO&INPIT
机译:解决的问题:为外周静脉给药提供稳定的输注制剂,其可以在常温下稳定保存,可以维持/改善维生素如维生素B1,维生素C等的营养状态的患者的营养状态。预期会恶化或恶化,并可以进一步有效地表现出抗氧化应激作用。含有浓度为50至150g / L的氨基酸的液体(B),其被分别容纳在通过可通信的分隔装置分隔的容器中。输液(A)不含亚硫酸盐,但含有维生素B1,且pH值为3至5。输液(A)和输液(B)中的至少一种含有维生素C,并且混合将输注液(A)和输注液(B)的液体设定为维生素C的浓度为200至400 mg / L,每天给予维生素C的剂量为400至800 mg。 C)2015,日本特许厅

著录项

  • 公开/公告号JP6014861B2

    专利类型

  • 公开/公告日2016-10-26

    原文格式PDF

  • 申请/专利权人 株式会社大塚製薬工場;

    申请/专利号JP20140234922

  • 发明设计人 黒田 晃功;三本 靖洋;木内 保太;

    申请日2014-11-19

  • 分类号A61K31/7004;A61K31/375;A61K31/51;A61K31/4415;A61K31/525;A61K31/198;A61K31/519;A61K9/08;A61P3/02;A61P43/00;A61P39/06;

  • 国家 JP

  • 入库时间 2022-08-21 14:42:52

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