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Novel ecdysone receptor / invertebrate retinoid X receptor-based inducible gene expression system

机译:基于新型蜕皮激素受体/无脊椎动物类维生素A X受体的诱导型基因表达系统

摘要

This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a novel ecdysone receptor/invertebrate retinoid X receptor-based inducible gene expression system and methods of modulating gene expression in a host cell for applications such as gene therapy, large-scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.
机译:本发明涉及生物技术或基因工程领域。具体地说,本发明涉及基因表达领域。更具体而言,本发明涉及基于蜕皮激素受体/无脊椎动物类维生素A X受体的新型可诱导基因表达系统,以及在宿主细胞中调节基因表达的方法,用于基因治疗,蛋白质和抗体的大规模生产,基于高通量的筛选试验,功能基因组学和转基因生物特性的调控。

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