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Lst-1 and / or compounds that are transported by the lst-2

机译:Lst-1和/或由Lst-2转运的化合物

摘要

PROBLEM TO BE SOLVED: To provide a new probe for cancer cell detection or hepatic cell detection and a medicament carrier comprising the compound and delivering a medicament to a cancer cell or a hepatic cell.SOLUTION: A new transport substrate for LST-1 as a transporter protein specifically expressing in a hepatic cell or for LST-2 as a transporter protein specifically expressing in a cancer cell is identified and the identified transport substrate of LST-1 and/or LST-2 is used as a probe for cancer cell detection or hepatic cell detection or a medicament carrier comprising the compound and delivering a medicament to a cancer cell or a hepatic cell.
机译:解决的问题:提供一种用于癌细胞检测或肝细胞检测的新探针以及包含该化合物并将药物递送至癌细胞或肝细胞的药物载体。鉴定在肝细胞中特异性表达的转运蛋白或作为癌细胞中特异性表达的转运蛋白LST-2,并将鉴定出的LST-1和/或LST-2的转运底物用作癌细胞检测或肝细胞检测或包含该化合物并将药物递送至癌细胞或肝细胞的药物载体。

著录项

  • 公开/公告号JP6021148B2

    专利类型

  • 公开/公告日2016-11-09

    原文格式PDF

  • 申请/专利权人 国立大学法人東北大学;

    申请/专利号JP20120197554

  • 发明设计人 阿部 高明;水井 佳治;

    申请日2012-09-07

  • 分类号A61K47/20;A61K47/22;A61K49/00;A61P35/00;A61K45/00;A61P1/16;

  • 国家 JP

  • 入库时间 2022-08-21 14:41:35

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