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Inspection method of atherosclerotic disease based on single nucleotide polymorphism on human chromosome 5p15.3

机译:基于人类染色体5p15.3单核苷酸多态性的动脉粥样硬化疾病检查方法

摘要

An atherosclerotic disease such as myocardial infarction or angina pectoris is detected by analyzing a single nucleotide polymorphism on human chromosome 5p15.3, and by associating results of the analysis with the risk of the onset thereof. Examples of the single nucleotide polymorphism on human chromosome 5p15.3 include a nucleotide corresponding to the nucleotide at position 61 in the nucleotide sequence of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3, and a polymorphism at a nucleotide which is in linkage disequilibrium with the above nucleotide.
机译:通过分析人染色体5p15.3上的单核苷酸多态性,并将分析结果与发病风险相关联,可以检测出诸如心肌梗塞或心绞痛等动脉粥样硬化疾病。人染色体5p15.3上的单核苷酸多态性的实例包括对应于SEQ ID NO:1,SEQ ID NO:2或SEQ ID NO:3的核苷酸序列中第61位的核苷酸的核苷酸,以及在与上述核苷酸连锁不平衡的核苷酸。

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