Anti-tumor divalent platinum complex and method for producing complex and complex ligand

摘要

A platinum complex containing 3-ketonecyclobutane-1,1-dicarboxylic acid as a leaving group and a method for producing the same. One of the platinum complexes is cis- [3-ketonecyclobutane-1,1-dicarboxylic acid group-diamine platinum (II)] (abbreviation is GSH-5, and its chemical structure is represented by formula (1)) And the other of the platinum complexes is cis- [3-ketone-1,1-cyclobutane-dicarboxylic acid group-trans-1,2-cyclohexanediamineplatinum (II)] (abbreviation is GSH-6. Chemical structure thereof Is represented by formula (2) and the carbon atom is in either the R or S configuration. [Selection figure] None