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Processes and compositions for enrichment based on methylation of fetal nucleic acids from maternal samples useful for non-invasive prenatal diagnosis
Processes and compositions for enrichment based on methylation of fetal nucleic acids from maternal samples useful for non-invasive prenatal diagnosis
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机译:基于来自孕妇样品的胎儿核酸的甲基化进行富集的方法和组合物,可用于非侵入性产前诊断
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摘要
Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuplodies.
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