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Use of a compound comprising a peptide comprising glycine-arginine-glycine-cysteic acid-threonine-proline in the manufacture of a medicament
Use of a compound comprising a peptide comprising glycine-arginine-glycine-cysteic acid-threonine-proline in the manufacture of a medicament
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机译:包含包含甘氨酸-精氨酸-甘氨酸-半胱氨酸-苏氨酸-脯氨酸的肽的化合物在制备药物中的用途
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摘要
Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH-CH(CH2- SO3H)COOH or Arg-Gly-NH-CH(CH2-SO3H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug-conjugates, pro-drugs and their derivatives. Also disclosed are methods for making and using such compounds including methods for inhibiting cellular adhesion to RGD binding sites or delivering other diagnostic or therapeutic agents to RGD binding sites in human or animal subjects.
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