Fibrosis susceptibility gene and its use

摘要

It discloses the identification of fibrosis susceptibility loci, detection of predisposition to fibrosis, diagnostics, and used for prognosis. Moreover, the present invention can be used to screen for drugs therapeutically effective I disclose the CTGF gene locus. In particular, in a sample from a subject, a method comprising the step of detecting the presence of an alteration in the CTGF gene locus, the present invention relates to a method for the presence of said alteration is indicative of the presence or predisposition fibrosis.