首页> 外国专利> Method for screening a compound that promotes or inhibits transport activity of OATP1B1, and method for measuring OATP1B1 expression level

Method for screening a compound that promotes or inhibits transport activity of OATP1B1, and method for measuring OATP1B1 expression level

机译:筛选促进或抑制OATP1B1转运活性的化合物的方法和测量OATP1B1表达水平的方法

摘要

The present invention provides a method of screening for a compound that enhances or inhibits the transport activity of OATP1B1, using dichlorofluorescein. The present invention also provides a use of dichlorofluorescein in measurement of the expression level of OATP1B1. The present invention further provides a method for measuring the expression level of OATP1B1 in test cells, using dichlorofluorescein. The present invention further provides a use of a kit including dichlorofluorescein and positive cells expressing OATP1B1 in measurement of the expression level of OATP1B1 in test cells.
机译:本发明提供了使用二氯荧光素筛选增强或抑制OATP1B1的转运活性的化合物的方法。本发明还提供了二氯荧光素在测量OATP1B1表达水平中的用途。本发明进一步提供了一种使用二氯荧光素来测量测试细胞中OATP1B1表达水平的方法。本发明进一步提供了包括二氯​​荧光素和表达OATP1B1的阳性细胞的试剂盒在测量测试细胞中OATP1B1的表达水平中的用途。

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