首页>
外国专利>
NOVEL SCORPION TOXIN ANALOGUE AND METHOD FOR TREATING AUTOIMMUNE DISEASES
NOVEL SCORPION TOXIN ANALOGUE AND METHOD FOR TREATING AUTOIMMUNE DISEASES
展开▼
机译:新型蝎COR毒素类似物和治疗自身免疫性疾病的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A novel peptide analogue of the Heterometrus spinnifer toxin HsTX1 is disclosed along with its application as, for example, a therapeutic agent for treating an autoimmune disease such as multiple sclerosis (MS) or rheumatoid arthritis (RA). The analogue comprises a peptide with an amino acid substitution at amino acid position 14 of the wild-type (WT) peptide sequence (or a position corresponding to position 14 of the WT peptide sequence). The analogue exhibits selectivity for Kv1.3 over Kv1.1 and other potassium channels relative to the WT peptide.
展开▼