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METHOD FOR PREPARING HEPATOCYTE AND METHOD FOR EVALUATING DRUG HEPATOTOXICITY OF INTEREST
METHOD FOR PREPARING HEPATOCYTE AND METHOD FOR EVALUATING DRUG HEPATOTOXICITY OF INTEREST
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机译:肝细胞的制备方法和对药物肝毒性的评估方法
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摘要
A method for preparing a hepatocyte includes the following steps: providing a liver progenitor cell, proliferating the liver progenitor cell in a medium supplemented with nicotinamide, insulin-transferrin-selenium (ITS) and EGF, and inducing the liver progenitor cell into the hepatocyte having a hepatic cord-like structure morphology. In one embodiment, the method further includes providing a pluripotent stem cell and differentiating the pluripotent stem cell into the liver progenitor cell.
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