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Multifunctional Metal Nanoparticles Having A Polydopamine-Based Surface and Methods of Making and Using the Same
Multifunctional Metal Nanoparticles Having A Polydopamine-Based Surface and Methods of Making and Using the Same
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机译:具有基于聚多巴胺的表面的多功能金属纳米颗粒及其制备和使用方法
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摘要
The present invention provides nanoparticles including a metallic core having a length along each axis of from 1 to 100 nanometers and a coating disposed on at least part of the surface of the metallic core, wherein the coating comprises polydopamine, along with methods for making and using such nanoparticles. The metallic core may be gold, silver or iron oxide and the polydopamine coating may have other substances bound to it, such as silver, targeting ligands or antibodies, or other therapeutic or imaging contrast agents. The disclosed nanoparticles can be targeted to cells for treating cancer or bacterial infections, and for use in diagnostic imaging.
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