SHAPE-MEMORY-ACTUATED MATERIALS FOR ACCELERATED HEALING OF ORTHOPEDIC INJURIES

摘要

A three component system for repairing critically sized bone defects having a first shape memory polymer (SMP) component formed as a scaffold that fills the defects, a second SMP component formed as a restricting sleeve that stabilizes and supports osseointegration and osteoconduction, and a third SMP component formed as a two-dimensional cell culture substate for engineering periosteal grafts.