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NANOCOMPOSITES, METHODS OF MAKING SAME, AND APPLICATIONS OF SAME FOR MULTICOLOR SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) DETECTIONS
NANOCOMPOSITES, METHODS OF MAKING SAME, AND APPLICATIONS OF SAME FOR MULTICOLOR SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) DETECTIONS
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机译:纳米复合材料,制造方法及其在多色表面增强拉曼光谱(SERS)检测中的应用
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摘要
A nanoagent for surface enhanced Raman spectroscopy (SERS) detection of a target of interest, includes one or more nanocomposites. The target of interest may include at least one tumor cell or at least one pathogen. Each nanocomposite includes at least one gold nanorod, a silver layer coated on a surface of the gold nanorod and having silver nanoparticles, a Raman reporter molecule layer assembled on the silver layer and having Raman reporter molecules, a pegylated layer coated on the Raman reporter molecule layer, and an antibody layer conjugated to the pegylated layer. The different nanocomposites of the nanoagent can be represented by different colors when SERS images are collected upon the nanoagent.
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