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Nanocomposites, methods of making same, and applications of same for multicolor surface enhanced raman spectroscopy (SERS) detections
Nanocomposites, methods of making same, and applications of same for multicolor surface enhanced raman spectroscopy (SERS) detections
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机译:纳米复合材料,其制备方法及其在多色表面增强拉曼光谱(SERS)检测中的应用
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摘要
A method of making at least one nanocomposite for surface enhanced Raman spectroscopy (SERS) detection of a target of interest includes forming at least one gold nanorod; coating a silver layer on an outer surface of the gold nanorod; assembling a Raman reporter molecule layer on the coated silver layer, wherein the Raman reporter molecule layer comprises Raman reporter molecules that are detectable by the SERS; coating a thiolated polyethylene glycol (PEG) layer on the assembled Raman reporter molecule layer; and conjugating the coated thiolated PEG layer with molecules of an antibody to make the at least one nanocomposite.
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