Methods and apparatus for analyzing test data in determining the effect of drug treatments

摘要

Methods and apparatus provide for: receiving pre-clinical data measured during drug treatment of a plurality of mammals including at least two treatment groups; performing at least one EXACT, non-parametric, statistical hypothesis test comparing the pre-clinical data for the at least two treatment groups; and performing a Multiple Comparison Procedure (MCP) on the pre-clinical data for at least two comparisons, where the EXACT, non-parametric, statistical hypothesis test and the MCP are conducted on the pre-clinical data to produce one or more p-values, each p-value representing whether an associated one of the treatment groups has experienced a statistically significant improvement or decline in one or more conditions of the mammals associated with the treatment.