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Method and means for enrichment, removal and detection of gram-positive bacteria
Method and means for enrichment, removal and detection of gram-positive bacteria
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机译:富集,去除和检测革兰氏阳性细菌的方法和手段
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摘要
The present invention relates to polypeptides comprising a enzymatically non-active cell wall binding domain of an endolysin or another cell wall lysing enzyme, and a sequence according to SEQ ID NO: 1 or derivatives thereof, wherein the polypeptide besides the cell wall binding domain comprises no further domains of an endolysin, as well as means for their preparation. The present invention further relates to methods for binding, enriching, removing from a sample, capturing and/or detecting bacteria, particularly gram positive bacteria.
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机译:本发明涉及包含内溶素或另一种细胞壁裂解酶的非酶活性细胞壁结合结构域的多肽,以及根据SEQ ID NO:1的序列或其衍生物,其中除细胞壁结合域之外的多肽还包括没有其他溶血素的结构域,以及其制备方法。本发明进一步涉及用于结合,富集,从样品中去除,捕获和/或检测细菌,特别是革兰氏阳性细菌的方法。
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