首页> 外国专利> Sorbent comprising on its surface a cationic or protonizable aliphatic residue for the purification of organic molecules

Sorbent comprising on its surface a cationic or protonizable aliphatic residue for the purification of organic molecules

机译:吸附剂在其表面上包含阳离子或可质子化的脂肪族残基,用于纯化有机分子

摘要

The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic application.
机译:本发明涉及一种包含固体载体材料的吸附剂,该固体载体材料的表面包含通式(I)的残基,其中该残基通过共价单键连接至任一固体颗粒表面上的官能团。支撑材料本身或固体支撑材料表面上的聚合物薄膜。此外,本发明涉及根据本发明的吸附剂在纯化有机分子,特别是在药学上优选在色谱应用中的药物活性化合物中的用途。

著录项

  • 公开/公告号US9452415B2

    专利类型

  • 公开/公告日2016-09-27

    原文格式PDF

  • 申请/专利权人 INSTRACTION GMBH;

    申请/专利号US201214344718

  • 申请日2012-09-17

  • 分类号B01J20/22;B01J20/286;B01D15/38;B01J20/32;C07D313;C07B63;C07D305/14;C07H3/02;C07H17/08;C07D215/18;C07D493/22;C07C37/82;A61K31/337;A61K31/365;A61K31/47;A61K31/573;A61K31/724;C07C211/09;C07C215/12;C07C225/06;C07D295/185;

  • 国家 US

  • 入库时间 2022-08-21 14:30:59

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