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Glycomimetics as Pseudomonas aeruginosa lectin inhibitors

机译：糖代谢药为铜绿假单胞菌凝集素抑制剂

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摘要

The present invention relates to fucose- and mannose-derived glycomimetics and their general use in prophylaxis or treatment of Pseudomonas aeruginosa infections including respiratory tract infections, urinary tract infections, nosocomial infections and chronic wound infections in a patient encompassing a patient suffering already from cystic fibrosis. Said glycomimetics are inhibitors of Pseudomonas aeruginosa lectin LecB. 展开▼

机译：本发明涉及岩藻糖和甘露糖衍生的糖模拟物及其在预防或治疗铜绿假单胞菌感染（包括呼吸道感染，尿路感染，医院感染和慢性伤口感染）中的一般用途。已经患有囊性纤维化的患者。所述的糖模拟物是铜绿假单胞菌凝集素LecB的抑制剂。展开▼

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公开/公告号US9371351B2

专利类型

公开/公告日2016-06-21

原文格式PDF

申请/专利权人 UNIVERSITÄT KONSTANZ;
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申请/专利号US201314391109

发明设计人 ALEXANDER TITZ;
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申请日2013-04-09

分类号C07H7/02;C07H7/04;C07H7/06;C07H15/04;C07D309/02;C07D309/10;C07D407/12;A61K31/351;A61K31/7028;A61K45/06;

国家 US

入库时间 2022-08-21 14:30:53

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